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Buffalo Sabres left wing Matt Moulson (26) celebrates his goal against the Calgary Flames with left wing Tyler Ennis (63) during the second period at First Niagara Center.Kevin Hoffman

Matt Moulson scored twice and Jhonas Enroth stopped 42 shots as the Buffalo Sabres beat the Calgary Flames 4-3 on Thursday night.

Zemgus Girgensons and Marcus Foligno also scored for the Sabres, while Tyler Ennis had three assists. Moulson's second goal of the game, on a pass from Ennis with 7:29 to go, broke the 3-all tie and gave the Sabres their second straight win.

Mark Giordano, Sean Monahan and David Jones scored for Calgary, which outshot Buffalo 45-19.

The Sabres have won four straight at home, and are 4-4 against the Pacific Division.

Monahan scored on a rebound at 3:14 of the third to give the Flames a 3-2 lead. Girgensons then tied it when he took a pass through the crease from Ennis and shot into an open net at 7:59.

After a tepid start, Girgensons faked Karri Ramo down to the ice before the Flames' goalie recovered to stop the centre's wrap around attempt.

And Paul Byron split two Sabres defencemen to earn a breakaway, but Enroth grabbed the high backhand shot and held it for a whistle.

The scoreless first period gave way to a four-goal second.

Ennis stripped the puck from TJ Brodie in the corner and found Moulson streaking to the net. Moulson wristed the puck over Ramo's left shoulder to make it 1-0 at the 5:54 mark.

With Foligno already in the penalty box for slashing, a delay of game penalty to Nicolas Deslauriers gave Calgary a two-man advantage and the Flames instantly capitalized with Giordano's slap shot goal to tie the score with 8:29 to go in the period.

Stafford made a highlight-reel play to restore Buffalo's lead. Using a body fake to lose Derek Engelland in the corner, Stafford skated around the net before sending a no-look pass through the crease to Foligno, who finished his chance with 5:19 remaining.

Foligno was denied a second goal by video review with 3:43 left when it was ruled he deflected Nikita Zadorov's shot from above the legal height.

Calgary took advantage of the disallowed goal when Jones stick-checked Josh Gorges in front of Enroth and flipped the puck past the Sabres goaltender to even the score with 2:54 to go.

NOTES: The line of Girgensons, Moulson and Ennis accounted for seven points for the Sabres. ... Enroth was playing in his 100th career game. ... Buffalo C Cody Hodgson was a healthy scratch. ... Matt Stajan missed the game for Calgary after returning from a knee injury two games ago ... This was the 100th game between the Sabres and Flames.

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